Saier Chemical
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| Melting Point | 145-148°C (lit.) |
| Boiling Point | 355.8±25.0°C (Predicted) |
| Density | 1.204±0.06 g/cm³ (Predicted) |
| Form | Solid |
| Color | White to off-white |
| Solubility | Soluble in DMSO (a little), methanol (a little) |
| Store | Sealed in dry, Room Temperature |
| Packaging | 25KG Bag |
Hazard Statement: Harmful if swallowed, can cause skin irritation and severe eye irritation.
Warning Statement: Do not eat, drink or smoke when using, wash skin thoroughly after handling, wear protective gloves, eye protection and face protection, etc.
It is primarily used as a key chemical intermediate in the synthesis of ketoprofen, a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation. It is also used to screen cobalt-containing nitrile hydratase.
It is synthesized from methyl 3-cyanomethylbenzoate by reacting it with dimethyl carbonate in the presence of potassium carbonate, followed by hydrolysis, acidification, crystallization, and final purification.
The product should be stored in a dry, tightly sealed container at room temperature to maintain its stability and quality.
It is a white to off-white solid with a melting point of 145-148°C, a density of approximately 1.204 g/cm³, and is slightly soluble in DMSO and methanol.
Wear protective gloves, eye and face protection, and wash skin thoroughly after handling. Do not eat, drink, or smoke when working with this substance, as it is harmful if swallowed and can cause skin and eye irritation.
The standard commercial packaging for 3-(1-cyanoethyl)benzoic acid is in 25KG bags.
